DNA Traits · Mind & behaviour
Extraversion questionnaire association
A questionnaire score for how outgoing and sociable people describe themselves.
What the research found
In the cited research, the T allele at rs3764002 was associated with lower extraversion questionnaire scores in the studied cohorts.
- CC
- Higher score
- CT
- Middle
- TT
- Lower score
- Evidence
- Multi-cohort GWAS at a previously reported WSCD2 locus
- Who was studied
- European-ancestry multi-cohort analyses including the US Million Veteran Program; the MVP component was predominantly older men
How common each genotype is
| Region | CCHigher score | CTMiddle | TTLower score |
|---|---|---|---|
| All regions2,504 people | 59% | 30% | 11% |
| Africa661 people | 97% | 2% | <1% |
| The Americas347 people | 70% | 27% | 3% |
| East Asia504 people | 21% | 49% | 30% |
| Europe503 people | 54% | 39% | 6% |
| South Asia489 people | 44% | 42% | 14% |
Among the 2,504 people of the 1000 Genomes Project, in five world regions. These percentages describe groups of people, never anyone’s chance of having a trait.
Through time
How often the studied letter was read in ancient people, era by era, in the region chosen.
| Before farmingbefore 6500 BC | 46%29 of 63 copies read |
|---|---|
| First farmers6500 to 3000 BC | 37%399 of 1,066 copies read |
| Bronze Age3000 to 1200 BC | 32%327 of 1,017 copies read |
| Iron Age and Antiquity1200 BC to AD 600 | 29%355 of 1,244 copies read |
| Middle AgesAD 600 to 1500 | 30%187 of 620 copies read |
| Today1000 Genomes | 26%261 of 1,006 copies |
Neanderthal and Denisovan genomes
- Altai Neanderthal
- No copies
- Vindija Neanderthal
- No copies
- Chagyrskaya Neanderthal
- No copies
- Denisovan
- No copies
Neanderthals and Denisovans carried the other letter, so this letter is younger than our split with them.
The marker
- Gene or region
- WSCD2 region
- Marker
- rs3764002
- Location
- Chromosome 12 · GRCh37 108,618,630 · GRCh38 108,224,853
- Letters studied
- C and T, with T as the studied allele
A DNA Traits report reads this marker in your raw DNA file and shows which of the three genotypes is yours, with how common it is. It counts the copies of the studied allele; it does not measure the trait itself.
- Marker
- WSCD2 region · rs3764002
- Location
- Chromosome 12 · GRCh37 108,618,630 · GRCh38 108,224,853
- Studied allele
- T
- Published statistic
- beta -0.0299 per T allele (SE 0.0045; the paper states no unit or standardisation), P 3.449e-11, T frequency 0.2577 (Supplementary Table 7, EUR meta-analysis of MVP with GPC phase 2) (Supplementary Table 7, rs3764002 row)
- 1000 Genomes Project phase 3, people with 0, 1 and 2 copies
- All regions 1480 / 761 / 263 · Africa 644 / 15 / 2 · The Americas 242 / 95 / 10 · East Asia 104 / 248 / 152 · Europe 274 / 197 / 32 · South Asia 216 / 206 / 67
What it cannot tell you
This small association concerns scores on self-reported personality questionnaires. A single marker cannot assess your personality, emotional state, intelligence, capability or mental health. It gives no personality score and says nothing about any mental-health condition. Only the studied C/T allele pair is interpreted.
A genome-wide investigation into the underlying genetic architecture of personality traits and overlap with psychopathology (Gupta et al., 2024)More in Mind & behaviour
- Neuroticism questionnaire association
- Agreeableness questionnaire research association
- Conscientiousness questionnaire research association
- Openness questionnaire research association
- Subjective well-being research association
- Hand preference, CRHR1 marker
- Hand preference, MAP2 marker
- Hand preference, FURIN marker
- Clapping in time to a beat
See your own two letters.
Upload the raw DNA file you already have. Your report reads this marker and every other card studied for you, each with its evidence and its limits.