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DNA Traits · Sleep & rhythms

Daytime napping (STK32A)

How often people nap during the day.

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Evidence · Replicated

What the research found

In the cited research, the A allele at rs10875622 was associated with more frequent self-reported daytime napping in the studied cohorts.

GG
Less often
AG
Middle
AA
More often
Slight effect

What the study found

In the study, each copy went with how often people nap, on a three-step scale from never or rarely to usually about 0.01 points higher on average.

UK Biobank and 23andMe research participants of European ancestry · 993,966 people · Supplementary Data 2
Evidence
Genome-wide association in UK Biobank with independent replication in 23andMe
Who was studied
UK Biobank and 23andMe research participants of European ancestry
1000 Genomes Project

How common each genotype is

How common each genotype is in the 1000 Genomes Project, by region
RegionGGLess oftenAGMiddleAAMore often
All regions2,504 people20%48%32%
Africa661 people20%47%33%
The Americas347 people22%51%27%
East Asia504 people13%48%39%
Europe503 people17%47%37%
South Asia489 people28%47%25%

Among the 2,504 people of the 1000 Genomes Project, in five world regions. These percentages describe groups of people, never anyone’s chance of having a trait.

rs10875622

The marker

Gene or region
STK32A
Marker
rs10875622
Location
Chromosome 5 · GRCh37 146,693,062 · GRCh38 147,313,499
Letters studied
A and G, with A as the studied allele

A DNA Traits report reads this marker in your raw DNA file and shows which of the three genotypes is yours, with how common it is. It counts the copies of the studied allele; it does not measure the trait itself.

Marker
STK32A · rs10875622
Location
Chromosome 5 · GRCh37 146,693,062 · GRCh38 147,313,499
Studied allele
A
Published statistic
Meta-analysis beta 0.0090 per A (SE 0.0009), P 6.24e-26; 23andMe replication 0.0075 (SE 0.0012), P 1.0e-9, n 541,333; UK Biobank 0.0105 (SE 0.0012), P 1.3e-17, n 452,633; A frequency 0.58 (Supplementary Data 1 and 2) (Supplementary Data 2)
1000 Genomes Project phase 3, people with 0, 1 and 2 copies
All regions 496 / 1195 / 813 · Africa 134 / 311 / 216 · The Americas 77 / 176 / 94 · East Asia 65 / 243 / 196 · Europe 83 / 236 / 184 · South Asia 137 / 229 / 123
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Limits

What it cannot tell you

Napping was self-reported on a three-step scale, and in UK Biobank the association was about twice as strong in men as in women.

Genetic determinants of daytime napping and effects on cardiometabolic health (Dashti et al., 2021)
The same topic

More in Sleep & rhythms

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