DNA Traits · Sleep & rhythms
Daytime napping (TLE4)
How often people nap during the day.
What the research found
In the cited research, the C allele at rs13284688 was associated with more frequent self-reported daytime napping in the studied cohorts.
- TT
- Less often
- CT
- Middle
- CC
- More often
What the study found
In the study, each copy went with how often people nap, on a three-step scale from never or rarely to usually about 0.01 points higher on average.
- Evidence
- Genome-wide association in UK Biobank with independent replication in 23andMe
- Who was studied
- UK Biobank and 23andMe research participants of European ancestry
How common each genotype is
| Region | TTLess often | CTMiddle | CCMore often |
|---|---|---|---|
| All regions2,504 people | 64% | 31% | 5% |
| Africa661 people | 65% | 32% | 3% |
| The Americas347 people | 73% | 23% | 3% |
| East Asia504 people | 74% | 25% | 1% |
| Europe503 people | 67% | 30% | 4% |
| South Asia489 people | 43% | 45% | 12% |
Among the 2,504 people of the 1000 Genomes Project, in five world regions. These percentages describe groups of people, never anyone’s chance of having a trait.
Through time
How often the studied letter was read in ancient people, era by era, in the region chosen.
| Before farmingbefore 6500 BC | 4%1 of 27 copies read |
|---|---|
| First farmers6500 to 3000 BC | 9%20 of 219 copies read |
| Bronze Age3000 to 1200 BC | 17%24 of 140 copies read |
| Iron Age and Antiquity1200 BC to AD 600 | 19%47 of 246 copies read |
| Middle AgesAD 600 to 1500 | 22%58 of 269 copies read |
| Today1000 Genomes | 19%187 of 1,006 copies |
Neanderthal and Denisovan genomes
- Altai Neanderthal
- Not read
- Vindija Neanderthal
- Not read
- Chagyrskaya Neanderthal
- No copies
- Denisovan
- Not read
The marker
- Gene or region
- TLE4 / PSAT1 region
- Marker
- rs13284688
- Location
- Chromosome 9 · GRCh37 81,727,018 · GRCh38 79,112,102
- Letters studied
- C and T, with C as the studied allele
A DNA Traits report reads this marker in your raw DNA file and shows which of the three genotypes is yours, with how common it is. It counts the copies of the studied allele; it does not measure the trait itself.
- Marker
- TLE4 / PSAT1 region · rs13284688
- Location
- Chromosome 9 · GRCh37 81,727,018 · GRCh38 79,112,102
- Studied allele
- C
- Published statistic
- Meta-analysis beta 0.0148 per C (SE 0.0011), P 1.33e-43, n 993,966; 23andMe replication 0.0144 (SE 0.0015), P 1.85e-21, n 541,333; UK Biobank 0.0151 (SE 0.0015), P 1.7e-23, n 452,633; C frequency 0.21 (Supplementary Data 1 and 2) (Supplementary Data 2)
- 1000 Genomes Project phase 3, people with 0, 1 and 2 copies
- All regions 1602 / 783 / 119 · Africa 428 / 211 / 22 · The Americas 255 / 80 / 12 · East Asia 372 / 125 / 7 · Europe 335 / 149 / 19 · South Asia 212 / 218 / 59
What it cannot tell you
Napping was self-reported on a three-step scale, and the average difference per copy is a small fraction of one step.
Genetic determinants of daytime napping and effects on cardiometabolic health (Dashti et al., 2021)More in Sleep & rhythms
- Morning preference association
- Snoring tendency association
- Sleep efficiency association
- Overnight sleep episodes association
- Sleep midpoint timing association
- Daytime napping association
- Daytime sleepiness association
- Difficulty sleeping association
- Morning preference (RGS16)
- Morning preference (AK5)
- Snoring (POC5)
- Snoring (TRAM1)
- Daytime napping (STK32A)
See your own two letters.
Upload the raw DNA file you already have. Your report reads this marker and every other card studied for you, each with its evidence and its limits.