DNA Traits · Sleep & rhythms
Overnight sleep episodes association
How many separate stretches a night of sleep is broken into, measured with a wrist tracker.
What the research found
In the cited research, the T allele at rs12714404 was associated with more accelerometer-inferred overnight sleep episodes in the studied cohorts.
- GG
- Fewer breaks
- GT
- Middle
- TT
- More breaks
What the study found
In the study, each copy went with higher number of separate sleep stretches per night, from a wrist tracker on average.
- Evidence
- Genome-wide association using seven-day wrist accelerometry
- Who was studied
- European-ancestry UK Biobank adults with seven-day wrist accelerometer measurements
How common each genotype is
| Region | GGFewer breaks | GTMiddle | TTMore breaks |
|---|---|---|---|
| All regions2,504 people | 42% | 40% | 17% |
| Africa661 people | 18% | 46% | 37% |
| The Americas347 people | 25% | 50% | 25% |
| East Asia504 people | 74% | 23% | 3% |
| Europe503 people | 50% | 43% | 7% |
| South Asia489 people | 46% | 42% | 12% |
Among the 2,504 people of the 1000 Genomes Project, in five world regions. These percentages describe groups of people, never anyone’s chance of having a trait.
Through time
How often the studied letter was read in ancient people, era by era, in the region chosen.
| Before farmingbefore 6500 BC | 16%9 of 58 copies read |
|---|---|
| First farmers6500 to 3000 BC | 32%137 of 422 copies read |
| Bronze Age3000 to 1200 BC | 25%80 of 322 copies read |
| Iron Age and Antiquity1200 BC to AD 600 | 29%205 of 716 copies read |
| Middle AgesAD 600 to 1500 | 28%215 of 762 copies read |
| Today1000 Genomes | 29%291 of 1,006 copies |
Neanderthal and Denisovan genomes
- Altai Neanderthal
- Not read
- Vindija Neanderthal
- Not read
- Chagyrskaya Neanderthal
- 2 copies
- Denisovan
- Not read
The marker
- Gene or region
- ACP1 / SH3YL1 region
- Marker
- rs12714404
- Location
- Chromosome 2 · GRCh37 282,462 · GRCh38 282,462
- Letters studied
- G and T, with T as the studied allele
A DNA Traits report reads this marker in your raw DNA file and shows which of the three genotypes is yours, with how common it is. It counts the copies of the studied allele; it does not measure the trait itself.
- Marker
- ACP1 / SH3YL1 region · rs12714404
- Location
- Chromosome 2 · GRCh37 282,462 · GRCh38 282,462
- Studied allele
- T
- Published statistic
- beta 0.037 SD per T allele (SE 0.005), P 1e-12; T frequency 0.283; passes the study's stricter 8e-10 threshold; 0.04 SD per copy (Table 3 (beta, SE, P, effect allele frequency); Methods, association testing paragraph (results reported on the inverse-normal scale))
- 1000 Genomes Project phase 3, people with 0, 1 and 2 copies
- All regions 1054 / 1012 / 438 · Africa 116 / 303 / 242 · The Americas 88 / 172 / 87 · East Asia 375 / 116 / 13 · Europe 249 / 217 / 37 · South Asia 226 / 204 / 59
What it cannot tell you
Sleep episodes were inferred from wrist movement and are not an exact count of conscious awakenings. This marker does not measure your sleep fragmentation, classify your sleep quality or test for a sleep disorder. Only the studied G/T allele pair is interpreted.
Genetic studies of accelerometer-based sleep measures yield new insights into human sleep behaviour (Jones et al., 2019)More in Sleep & rhythms
- Morning preference association
- Snoring tendency association
- Sleep efficiency association
- Sleep midpoint timing association
- Daytime napping association
- Daytime sleepiness association
- Difficulty sleeping association
- Morning preference (RGS16)
- Morning preference (AK5)
- Snoring (POC5)
- Snoring (TRAM1)
- Daytime napping (TLE4)
- Daytime napping (STK32A)
See your own two letters.
Upload the raw DNA file you already have. Your report reads this marker and every other card studied for you, each with its evidence and its limits.