DNA Traits · Sleep & rhythms
Snoring (POC5)
Whether people report snoring.
What the research found
In the cited research, the T allele at rs2307111 was associated with a higher tendency to report snoring in the studied cohort.
- CC
- Less often
- CT
- Middle
- TT
- More often
- Evidence
- Genome-wide association in UK Biobank; not significant in an independent Chinese cohort
- Who was studied
- UK Biobank adults of white British ancestry
How common each genotype is
| Region | CCLess often | CTMiddle | TTMore often |
|---|---|---|---|
| All regions2,504 people | 42% | 40% | 18% |
| Africa661 people | 85% | 14% | <1% |
| The Americas347 people | 22% | 52% | 26% |
| East Asia504 people | 28% | 51% | 21% |
| Europe503 people | 15% | 49% | 36% |
| South Asia489 people | 38% | 45% | 17% |
Among the 2,504 people of the 1000 Genomes Project, in five world regions. These percentages describe groups of people, never anyone’s chance of having a trait.
Through time
How often the studied letter was read in ancient people, era by era, in the region chosen.
| Before farmingbefore 6500 BC | 53%20 of 38 copies read |
|---|---|
| First farmers6500 to 3000 BC | 63%300 of 476 copies read |
| Bronze Age3000 to 1200 BC | 57%209 of 364 copies read |
| Iron Age and Antiquity1200 BC to AD 600 | 54%283 of 521 copies read |
| Middle AgesAD 600 to 1500 | 58%257 of 442 copies read |
| Today1000 Genomes | 60%608 of 1,006 copies |
Neanderthal and Denisovan genomes
- Altai Neanderthal
- No copies
- Vindija Neanderthal
- No copies
- Chagyrskaya Neanderthal
- No copies
- Denisovan
- No copies
Neanderthals and Denisovans carried the other letter, so this letter is younger than our split with them.
The marker
- Gene or region
- POC5
- Marker
- rs2307111
- Location
- Chromosome 5 · GRCh37 75,003,678 · GRCh38 75,707,853
- Letters studied
- C and T, with T as the studied allele
A DNA Traits report reads this marker in your raw DNA file and shows which of the three genotypes is yours, with how common it is. It counts the copies of the studied allele; it does not measure the trait itself.
- Marker
- POC5 · rs2307111
- Location
- Chromosome 5 · GRCh37 75,003,678 · GRCh38 75,707,853
- Studied allele
- T
- Published statistic
- BOLT-LMM beta 0.007667 per T (SE 0.00107), P 4.8e-13; minor allele C 0.3956 (Table 2). China Kadoorie Biobank look-up: beta 0.011 (SE 0.009), P 0.21 (Zhu et al., 2024, Supplementary Data 12) (Table 2)
- 1000 Genomes Project phase 3, people with 0, 1 and 2 copies
- All regions 1041 / 1001 / 462 · Africa 564 / 94 / 3 · The Americas 76 / 181 / 90 · East Asia 141 / 257 / 106 · Europe 75 / 248 / 180 · South Asia 185 / 221 / 83
What it cannot tell you
Snoring was taken from a partner's or housemate's complaint, so people who sleep alone count as non-snorers. The variant is also one of the stronger body mass index markers, which may carry part of the link.
Insights into the aetiology of snoring from observational and genetic investigations in the UK Biobank (Campos et al., 2020)More in Sleep & rhythms
- Morning preference association
- Snoring tendency association
- Sleep efficiency association
- Overnight sleep episodes association
- Sleep midpoint timing association
- Daytime napping association
- Daytime sleepiness association
- Difficulty sleeping association
- Morning preference (RGS16)
- Morning preference (AK5)
- Snoring (TRAM1)
- Daytime napping (TLE4)
- Daytime napping (STK32A)
See your own two letters.
Upload the raw DNA file you already have. Your report reads this marker and every other card studied for you, each with its evidence and its limits.