DNA Traits · Sleep & rhythms
Snoring tendency association
Whether people report snoring.
What the research found
In the cited research, the A allele at rs592333 was associated with a lower tendency to report snoring in the studied cohorts.
- GG
- More often
- AG
- Middle
- AA
- Less often
- Evidence
- Genome-wide association with self-reported snoring
- Who was studied
- European-ancestry UK Biobank adults
How common each genotype is
| Region | GGMore often | AGMiddle | AALess often |
|---|---|---|---|
| All regions2,504 people | 42% | 41% | 17% |
| Africa661 people | 27% | 46% | 27% |
| The Americas347 people | 35% | 46% | 19% |
| East Asia504 people | 71% | 25% | 4% |
| Europe503 people | 18% | 53% | 29% |
| South Asia489 people | 61% | 33% | 6% |
Among the 2,504 people of the 1000 Genomes Project, in five world regions. These percentages describe groups of people, never anyone’s chance of having a trait.
Through time
How often the studied letter was read in ancient people, era by era, in the region chosen.
| Before farmingbefore 6500 BC | 44%21 of 48 copies read |
|---|---|
| First farmers6500 to 3000 BC | 57%349 of 609 copies read |
| Bronze Age3000 to 1200 BC | 50%239 of 480 copies read |
| Iron Age and Antiquity1200 BC to AD 600 | 53%378 of 716 copies read |
| Middle AgesAD 600 to 1500 | 47%223 of 471 copies read |
| Today1000 Genomes | 56%561 of 1,006 copies |
Neanderthal and Denisovan genomes
- Altai Neanderthal
- 2 copies
- Vindija Neanderthal
- 2 copies
- Chagyrskaya Neanderthal
- 2 copies
- Denisovan
- No copies
The marker
- Gene or region
- DLEU7 region
- Marker
- rs592333
- Location
- Chromosome 13 · GRCh37 51,340,315 · GRCh38 50,766,179
- Letters studied
- A and G, with A as the studied allele
A DNA Traits report reads this marker in your raw DNA file and shows which of the three genotypes is yours, with how common it is. It counts the copies of the studied allele; it does not measure the trait itself.
- Marker
- DLEU7 region · rs592333
- Location
- Chromosome 13 · GRCh37 51,340,315 · GRCh38 50,766,179
- Studied allele
- A
- Published statistic
- BOLT-LMM beta -0.00906 per A allele (SE 0.001051) on the dichotomous snoring outcome (about 37% cases), P 1.0e-17; MAF 0.4423 (Table 2) (Table 2 (beta, SE, P, MAF); Results, GWAS paragraph (n 408,317; snoring 'taken as a dichotomous variable'))
- 1000 Genomes Project phase 3, people with 0, 1 and 2 copies
- All regions 1050 / 1021 / 433 · Africa 181 / 304 / 176 · The Americas 121 / 161 / 65 · East Asia 359 / 127 / 18 · Europe 89 / 267 / 147 · South Asia 300 / 162 / 27
What it cannot tell you
The study used self-reported snoring. This marker cannot tell you whether you snore, does not measure airway obstruction and is not a test for sleep apnea; it should not guide treatment. Only the studied A/G allele pair is interpreted.
Insights into the aetiology of snoring from observational and genetic investigations in the UK Biobank (Campos et al., 2020)More in Sleep & rhythms
- Morning preference association
- Sleep efficiency association
- Overnight sleep episodes association
- Sleep midpoint timing association
- Daytime napping association
- Daytime sleepiness association
- Difficulty sleeping association
- Morning preference (RGS16)
- Morning preference (AK5)
- Snoring (POC5)
- Snoring (TRAM1)
- Daytime napping (TLE4)
- Daytime napping (STK32A)
See your own two letters.
Upload the raw DNA file you already have. Your report reads this marker and every other card studied for you, each with its evidence and its limits.