DNA Traits · Nutrition & metabolism
Tea intake
How many cups of tea a day people usually drink.
What the research found
In the cited research, the A allele at rs9624470 was associated with slightly more cups of tea a day.
- GG
- Fewer cups
- AG
- Middle
- AA
- More cups
What the study found
In the study, each copy went with higher cups of tea a day on average.
- Evidence
- Genome-wide association in UK Biobank only
- Who was studied
- UK Biobank participants of European ancestry
How common each genotype is
| Region | GGFewer cups | AGMiddle | AAMore cups |
|---|---|---|---|
| All regions2,504 people | 37% | 44% | 19% |
| Africa661 people | 61% | 35% | 4% |
| The Americas347 people | 21% | 54% | 24% |
| East Asia504 people | 27% | 47% | 26% |
| Europe503 people | 17% | 48% | 35% |
| South Asia489 people | 49% | 41% | 10% |
Among the 2,504 people of the 1000 Genomes Project, in five world regions. These percentages describe groups of people, never anyone’s chance of having a trait.
The marker
- Gene or region
- ADORA2A / SPECC1L-ADORA2A
- Marker
- rs9624470
- Location
- Chromosome 22 · GRCh37 24,820,268 · GRCh38 24,424,300
- Letters studied
- A and G, with A as the studied allele
A DNA Traits report reads this marker in your raw DNA file and shows which of the three genotypes is yours, with how common it is. It counts the copies of the studied allele; it does not measure the trait itself.
- Marker
- ADORA2A / SPECC1L-ADORA2A · rs9624470
- Location
- Chromosome 22 · GRCh37 24,820,268 · GRCh38 24,424,300
- Studied allele
- A
- Published statistic
- beta -0.0262 (SE 0.0021) SD per G, P 2.0e-34 (Cole 2020 Supplementary Data 4); caffeine from tea beta -0.02534 (SE 0.00227) per G, P 6.8e-29 (Said 2020 Table S14); tea consumption beta 0.0126 per A, P 4e-16 (Zhong 2019 UK Biobank stage, via the GWAS Catalog); 0.03 SD per copy (Supplementary Data 4 (41467_2020_15193_MOESM5_ESM.xlsx), rs9624470 row, for the beta, SE and P; Supplementary Data 1 (41467_2020_15193_MOESM2_ESM.xlsx), 'cups of tea per day' row, for the N 448,060)
- 1000 Genomes Project phase 3, people with 0, 1 and 2 copies
- All regions 938 / 1098 / 468 · Africa 405 / 231 / 25 · The Americas 74 / 188 / 85 · East Asia 135 / 237 / 132 · Europe 85 / 243 / 175 · South Asia 239 / 199 / 51
What it cannot tell you
Studied only in UK Biobank, where tea drinking is common, and not yet confirmed in another population.
Comprehensive genomic analysis of dietary habits in UK Biobank identifies hundreds of genetic associations (Cole et al., 2020)More in Nutrition & metabolism
- Vitamin D concentration association
- Vitamin B6 concentration association
- Vitamin B12 concentration association
- Folate concentration association
- Retinol concentration association
- Alpha-tocopherol concentration association
- Serum iron concentration association
- Calcium concentration association
- Magnesium concentration association
- Blood selenium association
- Coffee intake
- Coffee intake
- Carbohydrate and protein intake
- Coffee intake
- Coffee intake
- Coffee intake
- Carbohydrate and protein intake
- Bitter drinks intake
- Fatty acid conversion
- Beta-carotene level
- Uric acid level
- Vitamin D level, CYP2R1 marker
- Bilirubin level
- Vitamin D level, DHCR7 marker
- Uric acid level, ABCG2 marker
- Red cell zinc level
- Vitamin B12 level, CUBN marker
- Vitamin B12 level, TCN1 marker
- Magnesium level, DCDC5 marker
- Transferrin level
- Morning cortisol level
- TSH level
- Iron level, TFR2 marker
- Omega-3 DHA share
- Calcium level, CYP24A1 marker
- Bilirubin level, SLCO1B3 marker
See your own two letters.
Upload the raw DNA file you already have. Your report reads this marker and every other card studied for you, each with its evidence and its limits.