Evidence · Not yet replicated

What the research found

In the cited research, the G allele at rs4864809 was associated with lower beard density.

AA: Denser
AG: Middle
GG: Sparser

Evidence: Discovery genome-wide association in men from an admixed Latin American cohort
Who was studied: Men in the CANDELA cohort from five Latin American countries

The research behind this card was done only in men, so it is part of a report requested as male.

1000 Genomes Project

How common each genotype is

How common each genotype is in the 1000 Genomes Project, by region
Region	AADenser	AGMiddle	GGSparser
All regions2,504 people	28%	46%	26%
Africa661 people	36%	47%	18%
The Americas347 people	12%	46%	42%
East Asia504 people	36%	46%	18%
Europe503 people	13%	46%	41%
South Asia489 people	36%	45%	19%

Among the 2,504 people of the 1000 Genomes Project, in five world regions. These percentages describe groups of people, never anyone’s chance of having a trait.

Ancient genomes

Through time

How often the studied letter was read in ancient people, era by era, in the region chosen.

Region

Through time: Europe
Before farmingbefore 6500 BC	80%33 of 41 copies read
First farmers6500 to 3000 BC	61%277 of 453 copies read
Bronze Age3000 to 1200 BC	64%204 of 320 copies read
Iron Age and Antiquity1200 BC to AD 600	60%278 of 460 copies read
Middle AgesAD 600 to 1500	55%193 of 349 copies read
Today1000 Genomes	64%643 of 1,006 copies

Neanderthal and Denisovan genomes

Altai Neanderthal: No copies
Vindija Neanderthal: Not read
Chagyrskaya Neanderthal: Not read
Denisovan: No copies

Neanderthals and Denisovans carried the other letter, so this letter is younger than our split with them.

For most ancient people only one of their two copies can be read, so these counts are copies read, not people. Close relatives, repeated samples and samples the archive marks as unreliable are left out. Damage in old DNA can fake this letter, so it is counted only from samples treated to remove that damage and from high-quality genomes. Ancient genomes from the Allen Ancient DNA Resource (AADR v66): 15,136 people.

rs4864809

The marker

Gene or region: LNX1 region
Marker: rs4864809
Location: Chromosome 4 · GRCh37 54,511,913 · GRCh38 53,645,746
Letters studied: A and G, with G as the studied allele

A DNA Traits report reads this marker in your raw DNA file and shows which of the three genotypes is yours, with how common it is. It counts the copies of the studied allele; it does not measure the trait itself.

Marker: LNX1 region · rs4864809
Location: Chromosome 4 · GRCh37 54,511,913 · GRCh38 53,645,746
Studied allele: G
Published statistic: P 1e-8 for rs4864809 (ancestral A > derived G) with beard thickness in CANDELA men (Table 1); within-country meta-analysis P 2.27e-7 (Supplementary Table 4); G has a negative coefficient in every country (Figure 2d, plotted only) (Table 1; Supplementary Table 4; Figure 2d)
1000 Genomes Project phase 3, people with 0, 1 and 2 copies: All regions 703 / 1151 / 650 · Africa 235 / 310 / 116 · The Americas 42 / 160 / 145 · East Asia 181 / 233 / 90 · Europe 67 / 229 / 207 · South Asia 178 / 219 / 92

Limits

What it cannot tell you

Beard density was assessed in men. This single-marker association does not predict facial hair for women or establish beard coverage, growth rate, or hormone levels.

A genome-wide association scan in admixed Latin Americans identifies loci influencing facial and scalp hair features (Adhikari et al., 2016)

The same topic

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