DNA Traits · Appearance
Finger length ratio (LDAH marker)
The length of the index finger compared with the ring finger.
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Evidence · Replicated
What the research found
In the cited research, the T allele at rs340600 was associated with a lower index to ring finger length ratio.
- GG
- Higher ratio
- GT
- Middle
- TT
- Lower ratio
Slight effect
What the study found
In the study, each copy went with index finger length as a percentage of ring finger length, left hand about 0.38 ratio points lower on average.
European ancestry discovery cohorts (ALSPAC, Generation R, QIMR, Raine, Rotterdam Study, TwinsUK) · 14,382 people · Table 2 (rs340600, discovery row); Supplementary Table S3; Discussion (European-only left-hand analysis, N 14 382)
- Evidence
- Genome-wide association with independent replication
- Who was studied
- European ancestry cohorts from the UK, the Netherlands and Australia; replicated in 23andMe research participants
1000 Genomes Project
How common each genotype is
| Region | GGHigher ratio | GTMiddle | TTLower ratio |
|---|---|---|---|
| All regions2,504 people | 58% | 32% | 10% |
| Africa661 people | 20% | 52% | 28% |
| The Americas347 people | 57% | 36% | 7% |
| East Asia504 people | 84% | 15% | <1% |
| Europe503 people | 67% | 31% | 3% |
| South Asia489 people | 75% | 22% | 3% |
Among the 2,504 people of the 1000 Genomes Project, in five world regions. These percentages describe groups of people, never anyone’s chance of having a trait.
Ancient genomes
Through time
How often the studied letter was read in ancient people, era by era, in the region chosen.
Region
Europe
| Before farmingbefore 6500 BC | 30%27 of 91 copies read |
|---|---|
| First farmers6500 to 3000 BC | 28%265 of 955 copies read |
| Bronze Age3000 to 1200 BC | 18%155 of 885 copies read |
| Iron Age and Antiquity1200 BC to AD 600 | 19%294 of 1,542 copies read |
| Middle AgesAD 600 to 1500 | 20%275 of 1,389 copies read |
| Today1000 Genomes | 18%180 of 1,006 copies |
Neanderthal and Denisovan genomes
- Altai Neanderthal
- No copies
- Vindija Neanderthal
- No copies
- Chagyrskaya Neanderthal
- No copies
- Denisovan
- No copies
Neanderthals and Denisovans carried the other letter, so this letter is younger than our split with them.
rs340600
The marker
- Gene or region
- LDAH (formerly C2orf43)
- Marker
- rs340600
- Location
- Chromosome 2 · GRCh37 20,892,006 · GRCh38 20,692,246
- Letters studied
- G and T, with T as the studied allele
A DNA Traits report reads this marker in your raw DNA file and shows which of the three genotypes is yours, with how common it is. It counts the copies of the studied allele; it does not measure the trait itself.
- Marker
- LDAH (formerly C2orf43) · rs340600
- Location
- Chromosome 2 · GRCh37 20,892,006 · GRCh38 20,692,246
- Studied allele
- T
- Published statistic
- beta −0.379 (SE 0.046) per T allele on 2D:4D x 100, P 1.38e-16, EAF 0.199 (Table 2, European discovery meta-analysis); 23andMe replication beta −0.043 (SE 0.005) on a three-level self-reported finger-length scale, P 1.81e-17, n 75,821 (Table 2); same direction in all six discovery cohorts, heterogeneity P 0.053 (Supplementary Table S3); the lead SNPs at the 12 replicated signals together explain 3.8% of the variance (Results) (Table 2 (rs340600, discovery row); Supplementary Table S3; Discussion (European-only left-hand analysis, N 14 382))
- 1000 Genomes Project phase 3, people with 0, 1 and 2 copies
- All regions 1456 / 806 / 242 · Africa 130 / 345 / 186 · The Americas 199 / 124 / 24 · East Asia 424 / 76 / 4 · Europe 336 / 154 / 13 · South Asia 367 / 107 / 15
Limits
What it cannot tell you
A single marker, one of many that shape finger proportions. Measured on the left hand.
Genome-wide association study identifies nine novel loci for 2D:4D finger ratio, a putative retrospective biomarker of testosterone exposure in utero (Warrington et al., 2018)The same topic
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