DNA Traits · Appearance

Nose bridge breadth association

How broad the bridge of the nose is, between the eyes.

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Evidence · Replicated

What the research found

In the cited research, the T allele at rs1852985 was associated with greater nose bridge breadth in the studied cohorts.

CC: Narrower
CT: Middle
TT: Broader

Slight effect

What the study found

In the study, each copy went with nose bridge breadth rating from photos, on a three level scale where higher is broader about 0.07 points higher on average.

Admixed Latin American CANDELA participants from Brazil, Chile, Colombia, Mexico and Peru · 5,958 people · Table 1; Supplementary Figure 1 (three levels coded 0 to 2)

Evidence: Genome-wide association with independent replication
Who was studied: Admixed Latin American CANDELA participants from Brazil, Chile, Colombia, Mexico and Peru

1000 Genomes Project

How common each genotype is

How common each genotype is in the 1000 Genomes Project, by region
Region	CCNarrower	CTMiddle	TTBroader
All regions2,504 people	68%	28%	4%
Africa661 people	70%	27%	3%
The Americas347 people	56%	34%	10%
East Asia504 people	57%	37%	6%
Europe503 people	76%	23%	1%
South Asia489 people	79%	20%	2%

Among the 2,504 people of the 1000 Genomes Project, in five world regions. These percentages describe groups of people, never anyone’s chance of having a trait.

rs1852985

The marker

Gene or region: SUPT3H / RUNX2 region
Marker: rs1852985
Location: Chromosome 6 · GRCh37 45,329,656 · GRCh38 45,361,919
Letters studied: C and T, with T as the studied allele

A DNA Traits report reads this marker in your raw DNA file and shows which of the three genotypes is yours, with how common it is. It counts the copies of the studied allele; it does not measure the trait itself.

Marker: SUPT3H / RUNX2 region · rs1852985
Location: Chromosome 6 · GRCh37 45,329,656 · GRCh38 45,361,919
Studied allele: T
Published statistic: effect 0.069 per T allele on the ordinal rating, P 6e-10, 0.71% of variance, n 5,958; independent replication P 5e-3 in 501 people (Table 1); quantitative follow-up effect 4.4e-4 (Procrustes-scaled landmark distance), P 2e-8, 1.18% of variance, n 2,955 (Table 2) (Table 1; Supplementary Figure 1 (three levels coded 0 to 2))
1000 Genomes Project phase 3, people with 0, 1 and 2 copies: All regions 1710 / 694 / 100 · Africa 460 / 178 / 23 · The Americas 196 / 117 / 34 · East Asia 289 / 187 / 28 · Europe 380 / 116 / 7 · South Asia 385 / 96 / 8

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Limits

What it cannot tell you

This small marker association concerns measured facial geometry in the research sample. It does not reconstruct your face, classify attractiveness or calculate a facial measurement. Only the studied C/T allele pair is interpreted.

A genome-wide association scan implicates DCHS2, RUNX2, GLI3, PAX1 and EDAR in human facial variation (Adhikari et al., 2016)

The same topic

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